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New Study Connects Intake of Dairy Milk With Greater Risk of Breast Cancer

New Study Connects Intake of Dairy Milk With Greater Risk of Breast Cancer

 
   Sex hormone may be responsible, but no significant associations found with cheese and yogurt.

   Intake of dairy milk is associated with a greater risk of breast cancer in women, according to a new study conducted by researchers at Loma Linda University Health in Loma Linda, California, United States.

   "Dairy, Soy, and Risk of Breast Cancer: Those Confounded Milks,” published in the International Journal of Epidemiology, found that even relatively moderate amounts of dairy milk consumption can increase women’s risk of breast cancer — up to 80 percent depending on the amount consumed.

   First author of the paper Gary E. Fraser said the observational study gives "fairly strong evidence that either dairy milk or some other factor closely related to drinking dairy milk is a cause of breast cancer in women.

   "Consuming as little as one-fourth to one-third cup of dairy milk per day was associated with an increased risk of breast cancer of 30 percent,” Fraser said. "By drinking up to one cup per day, the associated risk went up to 50 percent, and for those drinking two to three cups per day, the risk increased further to 70 to 80 percent.”

   Current U.S. dietary guidelines recommend three cups of milk per day. "Evidence from this study suggests that people should view that recommendation with caution,” Fraser said.

   This raises the possibility that dairy-alternate milks may be an optimal choice.

   Dietary intakes of nearly 53,000 North American women were evaluated for the study, all of whom were initially free of cancer and were followed for nearly eight years. Dietary intakes were estimated from food frequency questionnaires (FFQ), also repeated 24-hour recalls, and a baseline questionnaire with questions about demographics, family history of breast cancer, physical activity, alcohol consumption, hormonal and other medication use, breast cancer screening, and reproductive and gynecological history.

   By the end of the study period, 1,057 new breast cancer cases had appeared during follow-up. No clear associations were found between soy products and breast cancer, independent of dairy. But, when compared to low or no milk consumption, higher intakes of dairy calories and dairy milk were associated with greater risk of breast cancer, independent of soy intake. Fraser noted that the results had minimal variation when comparing intake of full fat versus reduced or non-fat milks; no important associations were noted with cheese and yogurt.

   "However,” he said, "dairy foods, especially milk, were associated with increased risk, and the data predicted a marked reduction in risk associated with substituting soymilk for dairy milk. This raises the possibility that dairy-alternate milks may be an optimal choice.”

   A hazardous effect of dairy is consistent with the recent Adventist Health Study-2 (AHS-2) report, suggesting that vegans but not lacto-ovo-vegetarians experienced less breast cancer than non-vegetarians.

   Fraser said the possible reasons for these associations between breast cancer and dairy milk may be the sex hormone content of dairy milk, as the cows are, of course, lactating, and often about 75 percent of the dairy herd is pregnant. Breast cancer in women is a hormone-responsive cancer. Further, intake of dairy and other animal proteins in some reports is also associated with higher blood levels of a hormone, insulin-like growth factor-1 (IGF-1), which is thought to promote certain cancers.

   "Dairy milk does have some positive nutritional qualities,” Fraser said, "but these need to be balanced against other possible, less helpful effects. This work suggests the urgent need for further research.”

   The study is part of the Adventist Health Study-2, a long-term health study exploring the links between lifestyle, diet, and disease among members of the Seventh-day Adventist Church. The Adventist Health Study is funded in part through the generosity of the Ardmore Institute of Health.

   The original version of this story was posted on the Loma Linda University Health news site.

By: Briana Pastorino, Loma Linda University Health News

SvetaASD 27-02-2020, 16:28 346 0

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